South Asian Research Journal of Natural Products 2021-01-11T03:39:17+00:00 South Asian Research Journal of Natural Products Open Journal Systems <p style="text-align: justify;"><strong>South Asian Research Journal of Natural&nbsp;Products</strong>&nbsp;aims to publish&nbsp;high-quality&nbsp;papers (<a href="/index.php/SARJNP/general-guideline-for-authors">Click here for Types of paper</a>) covering all aspects of research&nbsp;of naturally occurring compounds or the biology of living systems from which they are obtained.</p> Antioxidant and Antibacterial Activity of Essential Oil from Artemisia argyi Leaf during Different Collecting Stages 2021-01-05T04:08:43+00:00 Huan-Yang Li Wen-Shang Yan Jian-Guo Xu <p><em>Artemisia argyi</em> essential oil is a volatile aromatic substance with antioxidant and antibacterial activities. Here, we investigated the composition, antioxidant and antibacterial activities of essential oil from <em>A. argyi</em> in different collecting stages. The results showed that the essential oil extracted from <em>A. argyi</em> collected on June 7 (Dragon Boat Festival) had the highest extraction rate of 0.88% in five different collection periods. According to GC-MS analysis, there are 29, 29, 31, 28 and 31 different compounds detected in the essential oil of <em>A. argyi</em> at different collection stages, among which there are 19 kinds of the same compounds, and the components with high content include 1,8-cineole, β-thujone, 4-p-menth-1-en-8-ol, caryophyllene, caryphylleneoxide, etc. Furthermore, the results of functional activity analysis showed that the essential oil extracted from <em>A. argyi</em> collected on the day of Dragon Boat Festival has higher antioxidant and antibacterial activities.</p> 2021-01-05T04:07:59+00:00 ##submission.copyrightStatement## In-vitro Investigation on the Therapeutic Potential of Carica papaya Leaf Extract on Some Pathogenic Bacteria 2021-01-11T03:39:17+00:00 Attah, Friday E. Moses, Abalaka Adobu Ugbede Shadrach OludareTimon Tayo <p><em>Carica papaya </em>is one of the most valuable plants used for various purposes in medicinal field and ethnomedicine. The aim this study was to investigate the therapeutic potential of <em>C. papaya</em> leaf extract using cold maceration method with distilled water, methanol and petroleum-ether. Phytochemical screening of the extracts revealed the presence of the following:&nbsp; alkaloids, saponins flavonoids, steroids, cardiac glycosides and tannins. Antimicrobial activities of the extracts were determined by agar well diffusion method by measuring the diameters of zones of inhibition. In aqueous extract, <em>Klebsiella pneumonia</em> had the highest zone of inhibition (16±0.00 mm) followed by <em>Escherichia coli</em> and <em>Staphylococcus aureus</em> at 14±0.00 mm and 12±0.5 mm respectively. In methanol extracts, <em>E. coli.</em> had the highest zone of inhibition (15±00 mm) followed by <em>Staphylococcusaureus</em> (12±0.00 mm) while K. <em>pneumonia</em> had no inhibition.&nbsp; With Petroleum-ether, <em>Staphylococcusaureus</em> had the highest zone of inhibition (22±0.00 mm) followed by E. coli (0.13±0.00 mm) while K. <em>pneumonia</em> had no inhibition. It was clear that <em>C. papaya</em> had antimicrobial activity but varied with organism and extraction solvent. Therefore, for development of drugs, different extraction solvent and bacteria must be used in order to develop effective and tailored made antimicrobials to curb the menace of antibiotics resistance.</p> 2021-01-11T00:00:00+00:00 ##submission.copyrightStatement##