Comparative Phytochemical and Antioxidant Assay of Ipomoea aquatica and Telfairia occidentalis
Published: 2024-10-15
Page: 298-308
Issue: 2024 - Volume 7 [Issue 3]
Azibanasamesa D.C.Owaba *
Department of Pharmaceutical and Medicinal Chemistry, Faculty of Pharmacy, Niger Delta University, Wilberforce Island, Bayelsa State, Nigeria.
Abraham S. Eboh
Department of Biochemistry, Faculty of Basic Medical Science, Niger Delta University, Wilberforce Island, Bayelsa State, Nigeria.
Miracle Usman
Department of Pharmaceutical and Medicinal Chemistry, Faculty of Pharmacy, Niger Delta University, Wilberforce Island, Bayelsa State, Nigeria.
Paul U. Ugwuabor
Department of Pharmaceutical and Medicinal Chemistry, Faculty of Pharmacy, Niger Delta University, Wilberforce Island, Bayelsa State, Nigeria.
Uwemedimo F. Umoh
Department of Pharmacognosy and Natural Medicine, Faculty of Pharmacy, University of Uyo, Uyo, Akwa-Ibom State, Nigeria.
*Author to whom correspondence should be addressed.
Abstract
Some medicinal plants are known to possess antioxidant and nutritional properties. People living in the developing countries rely on the use of medicinal plants for treatment of several diseases. Ipomoea aquatica and Telfairia occidentalis have been reported to posses several medicinal potentials, such as antioxidant activity. The aim was to determine and compare the antioxidant properties of the two medicinal plants, and to carry out elemental assay of the crude plants and phytochemical profiling of 70% methanol extracts. The experiment involved collection, extraction, chemical and elemental profiling and antioxidant assessment. The present study revealed the presence of minerals such as K, Fe, Zn, Se, Cu, Mg, Na, Mn, Ca, Cr, B and P in these medicinal plants. The HPLC analysis showed the presence of bioactive components including flavonoids, tannins and alkaloids. The extracts had an IC50 of 190 µg/ml and 226.67µg/ml for Ipomoea aquatica and Telfairia occidentalis respectively in comparison to the standard drug ascorbic acid (616.67µg/ml). These medicinal plants are more potent in scavenging DPPH radical than ascorbic acid.
Keywords: Telfaira occidentalis, Ipomea aquatic, polyphenols antioxidant, elemental analysis