South Asian Research Journal of Natural Products

Exploration of the Mechanism of Pinellia ternata Inhibiting Oxidative Stress Based on Zebrafish Model

Zheng Wang

College of Life Sciences and Engineering, Southwest University of Science and Technology, China.

Yonghao Ping

College of Life Sciences and Engineering, Southwest University of Science and Technology, China.

Juanjuan Chen

College of Life Sciences and Engineering, Southwest University of Science and Technology, China.

Shijun Guo

College of Life Sciences and Engineering, Southwest University of Science and Technology, China.

Li Deng

College of Life Sciences and Engineering, Southwest University of Science and Technology, China.

Yi Huang *

College of Life Sciences and Engineering, Southwest University of Science and Technology, China.

*Author to whom correspondence should be addressed.

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Abstract

Pinellia ternata, as a toxic traditional Chinese medicine, contains various active ingredients such as alkaloids, which can inhibit oxidative stress mechanisms. The experiment used zebrafish models to study the changes and effects of oxidative stress levels in organisms, and explored the mechanism of Pinellia ternata in inhibiting oxidative stress, laying the foundation for the development of antioxidants using Pinellia ternata as raw material.

Keywords: Pinellia ternata, oxidative stress, zebrafish model, fluorescent probe

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